As a pharmacist (retired), it’s hard for me to express the depth of my outrage over the ivermectin smear campaign. And boy, has it been effective. I will never stop trying to get the truth out, but people can be quite skeptical. At least half think I’m nuts.
I do find it ironic that, of all the drugs that really work against this virus, it is ivermectin, very possibly one of the safest medications I have ever come across. The injustice that’s been perpetrated by the FDA (and their gang) isn’t at all funny, but imagining the “bad guys” sitting around, trying to come up with *some* angle from which to attack this wonder drug, does make me feel just a tiny bit better.
Have used "horse paste" against Covid with great success! Followed FLCCC early treatment protocol for dosing. I'm on a fixed income, and can't afford the outrageous price gouging being perpetrated by suppliers of a medicine that apparently can be manufactured for mere pennies per dose. Time to "get a haircut, and get a real job".
I live in South Africa where doctors freely subscribe Ivermectin. At my workplace of the 400 at least 180 were coerced into taking the shots. Within 10 days 1 died and many others got sick. It caught us off guard and caused most to refuse the jabs. On the second round it was even worse. 3 people died and many got sick. I did not take the jab but was also infected with large numbers of others who also did not take the jab. I almost died and after about a week took Ivermectin, zinc and aspirin. Within a day I was better and 2 days later I was out of bed.
Recently our government has pushed to remove Ivermectin from the shelves. I hope the world realizes that we are under attack by very evil entities who have planned this for a very long time. So greatful that influencial people are pushing back and waking others up.
Ivermectin is the best known drug for early and perhaps late treatment of COVID-19, for good reason. However, for the great majority of the population, it is not the most important and urgently needed treatment.
Most people who do not supplement vitamin D3 properly, and have not had plenty of ultraviolet B exposure in recent months (white skin - it does not work so well with brown or black skin) have circulating 25-hydroxyvitamin D levels in the 5 to 25 ng/mL range (12.5 to 62.5 nmol/L). There is very little vitamin D3 in food (fortified or not) or multivitamins.
Since UV-B light is generally only available in the middle of cloudless summer days, and since it always damages DNA and so raises the risk of skin cancer, the only practical way most people can attain at least the 50 ng/mL 125 nmol/L circulating 25-hydroxylase is to supplement with vitamin D3 cholecalciferol.
Please see the Quraishi et al. 2014 https://jamanetwork.com/journals/jamasurgery/fullarticle/1782085 graph at https://vitamindstopscovid.info/00-evi/ and all the other research articles cited there. This shows which shows the risk of post-operative infections rising from 2.5% for pre-operative 25-hydroxyvitamin D levels of 50 ng/mL or more to 25% for 18 ng/mL, which is a typical unsupplemented level in the absence of recent UV-B skin exposure.
70 to 100 IU (0.0175 to 0.025 mg) per kilogram bodyweight vitamin D3 a day will, over several months, attain 25-hydroxyvitamin D levels of 50 ng/mL or above for most people who are not suffering from obesity. See the derivation of these ratios, and higher ratios for those suffering from obesity at:https://vitamindstopscovid.info/00-evi/#06-ratios as recommended by New Jersey Professor of Medicine Sunil Wimalawansa https://www.mdpi.com/2072-6643/14/14/2997/htm and the FLCCC in their I-PREPARE and I-RECOVER Long COVID protocols: https://covid19criticalcare.com/covid-19-protocols/ .
For 70 kg 154lb, this is 0.125 to 0.175 mg (5000 to 7000 IU) vitamin D3 a day. Since this takes months to raise 25-hydroxyvitamin D levels, in clinical emergencies we need a much faster way of boosting 25-hydroxyvitamin D so the person's immune system can mount strong innate and adaptive responses, and to greatly reduce the risk of wildly dysregulated hyper-inflammatory, indiscriminate cell destroying responses.
25-hydroxvyitamin D does not act as a hormone. It is an essential input to immune cells' vitamin D based intracrine (inside each cell) and paracrine (to nearby cells) signaling systems, which are crucial to how individual immune cells respond to their changing circumstances. This is not related to hormonal signaling. (The kidneys convert 25-hydroxyvitamin D into a carefully controlled, very low and generally stable level of circulating 1,25-dihydroxyvitamin D, which acts as a hormone - a long distance signaling molecule in the bloodstream - to regulate the behaviour of multiple cell types which are involved in calcium-phosphate-bone metabolism.)
The best known method of boosting 25-hydroxyvitamin D is bolus (single, high dose) vitamin D3. For instance, for 70 kg BW, 10 milligrams (400,000 IU) vitamin D3 cholecalciferol will raise 25-hydroxyvitamin D levels from typical unsupplemented levels such as 18 ng/mL. safely over 50 ng/mL in, very approximately, 4 days. The delay is due to the limited capacity of hydroxylation enzymes in the liver.
Many doctors don't know this. They think that giving a patient 0.125 mg 5000 IU vitamin D in a clinical emergency will do the trick - but that takes months.
4 days is too long in clinical emergencies. The best approach is to use a single oral dose of 0.014 mg calcifediol per kg bodyweight, with vitamin D3 on subsequent days to support the initially raised level. Calcifediol _is_ 25-hydroxyvitamin D. It goes straight into circulation. For 70 kg this is 1 milligram.
This is the most important and urgently needed treatment for anyone with sepsis, COVID-19 (at any stage, the earlier the better), ARDS, influenza, Kawasaki disease or MIS-C.
Castillo et al. 2020 https://www.sciencedirect.com/science/article/pii/S0960076020302764 found that a single oral dose of 0.532 mg calcifediol for hospitalised COVID-19 patients was the main reason (the other was imperfect randomisation) for ICU admissions being reduced from 50% to 2% and deaths from 8% to zero.
Few doctors know about this. I wrote to Dr Peter McCullough about vitamin D a year or more ago. He replied that he already used vitamin D - but he was only using small daily quantities which take months to raise 25-hydroxyvitamin D levels substantialy.
I am not trying to indicate that ivermectin is any less valuable than it is depicted by those who understand and use it. However, rapid 25-hydroxyvitamin D repletion is more important and urgent, because the great majority of COVID-19 sufferers have only 1/10 to 1/2 of the 25-hydroxvyitamin D their immune system needs to function properly.
I feel like I'm waiting again. Sort of feels like 1975, 2 years after RvW sham was made a Federal Law, when people said, someone is going to pay. Really? 50 years later, Abortion is widespread as ever and the states that will outlaw it will blow money flying women in for free. I'm happy it was overturned but this "THE BAD GUYS" are going to pay thing, seems to be complete BULLSHIT if you ask me. I'm 49 years old and I can count the times on one hand when good won.
Wondering if anyone has used IVM with the recent "variants" and if they were successful...my brother used it for Delta, was able to drive himself to antibody appointment on Day 4! I take it when I travel monthly between WI and FL, and have yet to acquire CV
As a pharmacist (retired), it’s hard for me to express the depth of my outrage over the ivermectin smear campaign. And boy, has it been effective. I will never stop trying to get the truth out, but people can be quite skeptical. At least half think I’m nuts.
I do find it ironic that, of all the drugs that really work against this virus, it is ivermectin, very possibly one of the safest medications I have ever come across. The injustice that’s been perpetrated by the FDA (and their gang) isn’t at all funny, but imagining the “bad guys” sitting around, trying to come up with *some* angle from which to attack this wonder drug, does make me feel just a tiny bit better.
Edited to correct typo
…at least half *think* I’m nuts.
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Cheers good pharmacist. ❤
Thank you!❤️
You can also correct original comment and then delete the "edited" comment, whereupon I'll make mine disappear as well!
(Like it never happened. 😉 )
My pleasure.
Have used "horse paste" against Covid with great success! Followed FLCCC early treatment protocol for dosing. I'm on a fixed income, and can't afford the outrageous price gouging being perpetrated by suppliers of a medicine that apparently can be manufactured for mere pennies per dose. Time to "get a haircut, and get a real job".
I live in South Africa where doctors freely subscribe Ivermectin. At my workplace of the 400 at least 180 were coerced into taking the shots. Within 10 days 1 died and many others got sick. It caught us off guard and caused most to refuse the jabs. On the second round it was even worse. 3 people died and many got sick. I did not take the jab but was also infected with large numbers of others who also did not take the jab. I almost died and after about a week took Ivermectin, zinc and aspirin. Within a day I was better and 2 days later I was out of bed.
Recently our government has pushed to remove Ivermectin from the shelves. I hope the world realizes that we are under attack by very evil entities who have planned this for a very long time. So greatful that influencial people are pushing back and waking others up.
Ivermectin is the best known drug for early and perhaps late treatment of COVID-19, for good reason. However, for the great majority of the population, it is not the most important and urgently needed treatment.
Most people who do not supplement vitamin D3 properly, and have not had plenty of ultraviolet B exposure in recent months (white skin - it does not work so well with brown or black skin) have circulating 25-hydroxyvitamin D levels in the 5 to 25 ng/mL range (12.5 to 62.5 nmol/L). There is very little vitamin D3 in food (fortified or not) or multivitamins.
Since UV-B light is generally only available in the middle of cloudless summer days, and since it always damages DNA and so raises the risk of skin cancer, the only practical way most people can attain at least the 50 ng/mL 125 nmol/L circulating 25-hydroxylase is to supplement with vitamin D3 cholecalciferol.
Please see the Quraishi et al. 2014 https://jamanetwork.com/journals/jamasurgery/fullarticle/1782085 graph at https://vitamindstopscovid.info/00-evi/ and all the other research articles cited there. This shows which shows the risk of post-operative infections rising from 2.5% for pre-operative 25-hydroxyvitamin D levels of 50 ng/mL or more to 25% for 18 ng/mL, which is a typical unsupplemented level in the absence of recent UV-B skin exposure.
70 to 100 IU (0.0175 to 0.025 mg) per kilogram bodyweight vitamin D3 a day will, over several months, attain 25-hydroxyvitamin D levels of 50 ng/mL or above for most people who are not suffering from obesity. See the derivation of these ratios, and higher ratios for those suffering from obesity at:https://vitamindstopscovid.info/00-evi/#06-ratios as recommended by New Jersey Professor of Medicine Sunil Wimalawansa https://www.mdpi.com/2072-6643/14/14/2997/htm and the FLCCC in their I-PREPARE and I-RECOVER Long COVID protocols: https://covid19criticalcare.com/covid-19-protocols/ .
For 70 kg 154lb, this is 0.125 to 0.175 mg (5000 to 7000 IU) vitamin D3 a day. Since this takes months to raise 25-hydroxyvitamin D levels, in clinical emergencies we need a much faster way of boosting 25-hydroxyvitamin D so the person's immune system can mount strong innate and adaptive responses, and to greatly reduce the risk of wildly dysregulated hyper-inflammatory, indiscriminate cell destroying responses.
25-hydroxvyitamin D does not act as a hormone. It is an essential input to immune cells' vitamin D based intracrine (inside each cell) and paracrine (to nearby cells) signaling systems, which are crucial to how individual immune cells respond to their changing circumstances. This is not related to hormonal signaling. (The kidneys convert 25-hydroxyvitamin D into a carefully controlled, very low and generally stable level of circulating 1,25-dihydroxyvitamin D, which acts as a hormone - a long distance signaling molecule in the bloodstream - to regulate the behaviour of multiple cell types which are involved in calcium-phosphate-bone metabolism.)
The best known method of boosting 25-hydroxyvitamin D is bolus (single, high dose) vitamin D3. For instance, for 70 kg BW, 10 milligrams (400,000 IU) vitamin D3 cholecalciferol will raise 25-hydroxyvitamin D levels from typical unsupplemented levels such as 18 ng/mL. safely over 50 ng/mL in, very approximately, 4 days. The delay is due to the limited capacity of hydroxylation enzymes in the liver.
Many doctors don't know this. They think that giving a patient 0.125 mg 5000 IU vitamin D in a clinical emergency will do the trick - but that takes months.
4 days is too long in clinical emergencies. The best approach is to use a single oral dose of 0.014 mg calcifediol per kg bodyweight, with vitamin D3 on subsequent days to support the initially raised level. Calcifediol _is_ 25-hydroxyvitamin D. It goes straight into circulation. For 70 kg this is 1 milligram.
This is the most important and urgently needed treatment for anyone with sepsis, COVID-19 (at any stage, the earlier the better), ARDS, influenza, Kawasaki disease or MIS-C.
Castillo et al. 2020 https://www.sciencedirect.com/science/article/pii/S0960076020302764 found that a single oral dose of 0.532 mg calcifediol for hospitalised COVID-19 patients was the main reason (the other was imperfect randomisation) for ICU admissions being reduced from 50% to 2% and deaths from 8% to zero.
Few doctors know about this. I wrote to Dr Peter McCullough about vitamin D a year or more ago. He replied that he already used vitamin D - but he was only using small daily quantities which take months to raise 25-hydroxyvitamin D levels substantialy.
I am not trying to indicate that ivermectin is any less valuable than it is depicted by those who understand and use it. However, rapid 25-hydroxyvitamin D repletion is more important and urgent, because the great majority of COVID-19 sufferers have only 1/10 to 1/2 of the 25-hydroxvyitamin D their immune system needs to function properly.
I feel like I'm waiting again. Sort of feels like 1975, 2 years after RvW sham was made a Federal Law, when people said, someone is going to pay. Really? 50 years later, Abortion is widespread as ever and the states that will outlaw it will blow money flying women in for free. I'm happy it was overturned but this "THE BAD GUYS" are going to pay thing, seems to be complete BULLSHIT if you ask me. I'm 49 years old and I can count the times on one hand when good won.
Wondering if anyone has used IVM with the recent "variants" and if they were successful...my brother used it for Delta, was able to drive himself to antibody appointment on Day 4! I take it when I travel monthly between WI and FL, and have yet to acquire CV